Oak Bioscience is a privately held contract research company serving the life science and pharmaceutical communities. Founded and managed by a group of experienced Silicon Valley biotech veterans, the company aims to help our customers simplify and accelerate Antibody and Aptamer (DNA Aptamer, RNA Aptamer, XNA Aptamer) biomolecule research and development projects. Our team has extensive experience in antibody engineering and chimeric antigen receptor engineering, aptamer development and CRISPR/Cas9 based genome engineering. It’s our goal to deliver reliable and affordable research services to the community.

Key Services

1. Antibody Engineering

Antibody Sequencing
Antibody Library Construction
Phage Display Library Panning
Recombinant Antibody Production
Antibody Fragment scFv Fab VHH Construction
Bispecific Antibody (BsAb) Design and Production
Antibody Humanization
Antibody Affinity Maturation
Antibody Isotype/Class Switching
Antibody Epitope Mapping
Antibody Generation through Single B Cell Technologies
Stable Cell Line Development

2. Chimeric Antigen Receptor Engineering

scFv and VHH selection from phage display libraries for CAR construction
CAR Design and Optimization
Generation of CAR-T Cell for Functional Testing

3. Aptamer Development

Nucleic Acid Aptamers

Peptide Aptamers

4. Genome Engineering by CRISP/Cas9 System

sgRNA and donor plasmids design and construction
Gene knockout and knockin cell line generation